Fractones form a micronenvironmental niche for cells in all animals including marine invertebrates. Using fractones markers and immunofluorescence microscopy, we have visualized fractones in arthropodes and sponges. We hypothesize that marine animal-associated fractones are found in tissues or organs that respond to a challenge (pollution, wound, change of climate, infection by fungi….).
The presence of fractones will be investigated to determine which types of changes are induced by a challenge and whether fractones are involved in the response to this challenge. Understanding basic mechanisms underlying the response to an environmental challenge will allow us to design innovative therapies to boost the self-response of the animal and help restoring the animal health and well-being.
A collaboration with Charlotte Corporeau, IFREMER, Brest, has started in this direction.